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This predicted S. pombe protein was not functionally characterized before.
Thus, we may state that PPC was not functionally relevant after MFG, as our fMRI EC data would seem to predict.
Also, human IL-10 is functionally active on a mouse mast cell line, but mouse IL-10 was not functionally active on a human B cell line [7].
Finally, CD44v7-10, although it was not functionally significant for growth, may be a target for chemosensitization.
Although one E2F1 binding site was predicted in the MMP-9 promoter, luciferase analysis indicated that this binding site was not functionally required.
Although circulating thyroid hormone levels were low, liver enzymes responsive to thyroid hormone levels were elevated, suggesting that thyroidal homeostasis was not functionally compromised.
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Furthermore, they indicate that phosphorylation at this residue is not functionally involved in those APP-mediated functions that prevent (NMJ) defects and early lethality in APLP2 null mice.
In fact, genes are not functionally independent; they work in synergy to perform biological function.
There remain a significant portion or rice genes that are not functionally redundant, as reflected in the recovery of loss-of-function mutants.
However, many of these genes are not functionally characterized and are annotated as hypothetical with no defined function.
As mentioned by the reviewers, our main point is that the two ATPase active sites are not functionally equivalent, suggesting that they modulate different steps in cohesin function.
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CEO of Professional Science Editing for Scientists @ prosciediting.com