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Then, the sketch contour of the 3D scan data on the lateral X-ray image was modified manually or adjusted automatically according to some aesthetic statistical data, to drive the simulation in real time by the state-of-the-art Laplacian surface deformation method.
The alignment was modified manually using MacClade 3.08 [57] and exported in NEXUS format for further analysis with the final alignment containing 3261 sites.
The multiple sequence alignment generated by ClustalX was modified manually and the conserved sequences were annotated according to the results of SMART and Pfam searches.
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To assess the feasibility, a 26-gauge Quincke spinal needle (B. Braun, Melsungen, Germany) has been modified manually.
As mismatches between PET and CT scans were identified in two patients (#4 and #9), the co-registrations were modified manually based on the PET images.
Alignments were modified manually if necessary.
Gene symbols were modified manually to fit the platform annotation.
This file may be modified manually to generate user-defined colors and shapes.
SNP clusters were modified manually, to refine cluster positions when necessary.
These values can be modified manually, and simulation can be rerun by clicking the "Simulate with new parameters" button.
Even though the number of samples to draw as line plots can be modified manually (see below), the statistical analysis is performed with the complete dataset.
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