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In the antimalarial test, the crude ethanolic root bark extract was mildly active against the multidrug resistant K1 and chloroquine sensitive NF 54 strains of Plasmodium falciparum, with IC50 values of 9.9 and 13 μg/mL, respectively [3].
Aqueous fraction was mildly active only against S. aureus with mean zone of inhibition 11.6 mm.
Clinical severity at entry was mildly active in 10 patients and moderately active in 4 patients.
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Disease activity of SLE patients was defined based on the Systemic Lupus Erythematosus Disease Activity Index 2000 SLEDAII 2000) [ 36- 38] in 101 patients: 6 of them had no activity (SLEDAI score 0), 35 were mildly active (0 < SLEDAI ≤ 5), 41 had moderate disease activity (5 < SLEDAI ≤ 10), 14 were highly active (10 < SLEDAI ≤ 20), and 5 had very high activity (SLEDAI > 20).
Bone mineral mass is higher in children who are physically active than in those who are mildly active [ 3], and higher in children who participate in activities that generate high impact forces than in those who engage in activities that impart lower impact forces [ 4- 6].
Bone mineral mass is higher in physically active children than in those who are mildly active [ 9], and higher in children who participate in activities that generate high impact forces than in those who practise activities with lower impact forces [ 10- 12].
Ti-complexes 4 7 (Fig. 2) are mildly active for ethylene polymerization in the presence of methylaluminoxane (MAO) as a co-catalyst [46].
While UPR is mildly active under fasting presumably to attenuate protein synthesis as previously suggested [26], our data showed a 3-fold increase of IRE1α phosphorylation, i.e. UPR, to enhance ER homeostasis in preparation for an upcoming wave of protein synthesis.
An indole spermidine alkaloid, didemnidine B, was described in the New Zealand ascidian Didemnum sp. Evaluation of the compound against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, L. donovani, and Plasmodium falciparum K1 chloroquine-resistant strain indicated didemnidine B to be mildly active toward the malaria parasite with IC50 value of 15 μM [ 70].
It has been observed that the Arg206His mutation causes the ACVR1 protein to be mildly constitutively active [11].
The abdomen was mildly distended; surgical incisions were intact and healing nicely and there was no evidence of active infection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com