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That number was markedly down from 1997, when 145 people died in fires in New York.
Business at the shops in the Citigroup Center, at 53rd Street and Lexington Avenue, one of the institutions identified as a possible target of an attack, was markedly down as tight security restricted access for customers.
Expression of endogenous Tiam1 was markedly down regulated by transfection with pSuper-Tiam1 RNAi, whereas the expression of β-tubulin was unaffected as revealed by immunoblotting (Figure 1C).
In contrast, expression of E-cadherin RNA was markedly down regulated by 2.75 fold compared to non-sensitized mice, in gluten-sensitized plus indomethacin-treated mice.
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As shown in Figure 4D, the MI/R injury significantly up-regulated the gp91phox expression, but this was markedly down-regulated by the BBR treatment.
This analysis indicated that CD30 was markedly down-regulated during the first week of differentiation, and the down-regulation of CD30 was faster than that of TRA-1-60.
The results showed that TGF-β was markedly down-regulated in the fibrotic kidney of the RBP-J cKO mice as compared with the control (Fig. 2A and 2B).
RT-qPCR results of the antioxidant genes in jejunal mucosa showed that compared to G1, the thioredoxin reductase (TRX) gene expression in G2 was markedly down-regulated, while NAD(P H: quinone oxidoreductase 1 (NQO-1) transcription was up-regulated.
We found that expression of genes encoding transcription factors involved in photoreceptor development, including Crx, Nrl, Nr2e3, Esrrb, and NeuroD, was markedly down-regulated in the Otx2 CKO at both P1 and P12.
In the present study, the expression level of VGF in postmortem spinal cords of sporadic ALS patients was markedly down-regulated, but typically expressed at high levels in the spinal cords of the control patients in any sections cervical 7 (C7), thoracic 8 (T8), and lumbar 4 (L4), respectively (Fig. 5E).
Moreover, proteins participating in the thiol redox were regulated in the root apoplast of rice seedlings treated with low-dose H2O2, of which the flavin-containing monooxygenase (FMO, spot 40) was markedly down-regulated, while protein disulfide-isomerase (PDI, spot 41) was up-regulated at 600 µM H2O2 concentration (Table S1 and Figure S2B).
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