In contrast, ZEB2 was markedly hypomethylated in the 468LN cells, in contrast with the 468GFP cells (1% versus 68% methylation), whereas SNAI2 showed only moderate overall DNA methylation differences (65% versus 61%) between the cell lines.
Compared to other optical minigastrin probes, in vivo tumour-to-background contrast was markedly increased.
In contrast, infection was markedly reduced in all of the superbug-infected mice treated with SNAPPs and all of the mice in the SNAPP group survived.
In contrast, CRP was markedly increased in patients undergoing short- and long-term hemodialysis.
In contrast, staining was markedly increased in CADASIL vessels and moreover restricted to granules reminiscent of Notch3-ECD deposits, as most clearly seen in capillaries.
In contrast, there was markedly less fibrosis and inflammation in DHA-pretreated mice and their lung structure showed only minimal damage.
Of note, the adipocyte specific isotype of PPARγ, PPARγ2, was markedly upregulated during adipogenesis in contrast to a previous report in which cells (Gemmis et al., 2006) from second trimester amniotic fluid were used.
Contrast enhancement was markedly reduced following anti-tumour necrosis factor-α therapy, consistent with other reports that this cytokine plays a major role in psoriatic skin and joint pathology [ 34].
In contrast, the SUVR was markedly higher in tumours than in granulomas (50 min/2 min, 0.72 ± 0.06 and 0.56 ± 0.05, respectively) with no overlap.
In contrast, the 2TCM was markedly preferred and necessary for fitting low specific-binding regions, where a worse VT agreement (17.6% difference) and significant VT differences between the models (p < 0.005) were seen.
In contrast, Nkd1G2A-GFP was markedly less active in this assay (Fig. 1H,I).
