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Hypertension was manageable with antihypertensive agents.
Although nausea and vomiting also occurred, it was manageable with routine antiemetic therapy.
The remaining three patients suffered from grade 2 osteonecrosis, which was manageable with minor sequestrectomy.
Diarrhoea was manageable with loperamide and usually was self-limiting, requiring no medication in the 14 drug-free days.
Diarrhea was typically transient, mostly Grade 1/2, occurring early during treatment, and was manageable with antidiarrheal medication.
Grade three hypertension was more frequent with bevacizumab (16% versus 3%) but was manageable with anti-hypertensive drugs, and did not lead to any discontinuation of treatment.
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"These boats are very fast but they are manageable with the right people and experience.
But, he added, "there are always going to be temperamental quirks, and those are manageable with the right coaching".
The flow from the outskirts so far has been manageable, with less than 1,000 people crossing into Iraqi- or Kurdish-controlled areas on Tuesday.
Asked about their ability to live where they do if Mrs. Stahl also worked in Manhattan, Mr. Stahl said, "Our both commuting into the city wouldn't be manageable with very small children".
The government says this is manageable with greater front-line productivity and savings in back and middle offices.
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