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He said it was "less efficacious for the real economy than most people suppose".
In the study by Bianco et al. [46] dedicated to headache patient management by general practitioners in Italy, less than half (46.7%) of the GPs modified the treatment when new scientific evidence indicated that its use for a patient was less efficacious that the new one.
They reported improved long-term glucose and insulin homeostasis by CD3 antibody depletion in obese B6 mice with concomitant restoration of epididymal Tregs; treatment was less efficacious in an ob/ob model.
For each outcome category, the SP treatment was less efficacious than the AQ treatment.
Mifepristone, however, was less efficacious in preventing escape of SK-OV-3 cells.
Treatment of animals with 9cRA was less efficacious than in animals not undergoing hormone stimulation.
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Platelet transfusions given to patients with fever or systemic inflammation are less efficacious.
Taken together, these studies suggest that cytisine and varenicline induce a similar increase in dopamine levels, but both these drugs are less efficacious than nicotine.
Colonoscopy may be less efficacious in reducing colorectal cancer mortality in the proximal compared with the distal colon.
Parents with a history of smoking and parents of adolescents who had tried smoking were less efficacious, held weaker antismoking beliefs, and less often reported household smoking rules.
Counter-intuitively, there are situations in which earlier inoculation can be less efficacious, and simultaneous inoculation with antibiotics can be detrimental.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com