While signaling within the cascade is largely linear, the terminal MAPK usually has a large number of substrates, whose phosphorylation kinetics and localization contribute to the generation of specific biological outputs [ 35, 36].
"Three-way catalysts represent but one obvious example of what is largely linear, take-make-dispose manufacturing process, from which one might want to move".
The slopes are largely linear, which indicates that this is a first-order reaction.
As expected, the droplet diameter increases regularly with opening time, the relation being largely linear and showing varying degrees of "coffee ring effect" with the temperature.
The response of the crystal was found to be largely linear over the upper 95% of the dynamic range, the deviations at lower energies can be attributed to the shortcomings of the PMT.
The normal probability plots were largely linear, indicating symmetrical distributions with coefficients of variation ranging from 0.15 to 0.40.
Despite variations between time-points (mostly below or barely reaching the 5-point cut-off except for emotional functioning) the changes were largely linear improvements.
More recently, it has been suggested that the response dynamics of OSNs in C. elegans and primary thermosensory neurons in the Drosophila larva are largely linear (Kato et al., 2012; Klein et al., 2015).
The path traced across this map by influenza A (H3N2) from 1968 until present is largely linear, showing serial replacement of one strain by another; there are no major bifurcations of antigenic phenotype [ 9].
The stability of the microfocused beam has been characterized, resulting in a drift in position which is largely linear and of the order of a few microns per 12 h, roughly corresponding to the time necessary to acquire one map.
