This result is consistent with our findings that VEGF121/rGel is cytotoxic only to VEGFR-2-expressing endothelial cells [ 10] and is internalized only into endothelial cells that express VEGFR-2 but not VEGFR-1 (this study).
The more favorable N 37 value of approximately 3,000 decays per cell (varying from 1,760 to 3,733) for different specific activities used, obtained for MNT-mediated delivery of 125I]SGMIB, can be attributed to the fact that the MNT was designed not only to be internalized, but also to undergo nuclear targeting.
It was previously suggested that among the three defined natriuretic peptide receptors, only NPRC was internalized in a ligand-dependent manner [ 19, 20].
While 53.3 % of the total cellular activity was found to be internalized for [68Ga]pentixafor, only 17.5%% of the total cellular activity was internalized in the case of [68Ga]NOTA-pentixafor.
The only published study concerning stigma among individuals with schizophrenia was internalized stigma [ 24].
The only place where conventional, integer-based arithmetic can be found in the GF1 is the program register, P, where it was internalized within the relevant counter chips.
This external condition was internalized.
In vitro studies indicated that PEG-coated cationic liposomes were internalized not only by tumor cells but also by endothelial cells, and consequently its l-OHP formulation displayed higher cytotoxicity towards both cell types as compared with l-OHP containing PEG-coated neutral liposomes.
In the presence of NaAz, ITs cannot be internalized, they only bind to antigens on the cell surface.
This group suggested that the difference in accumulation is because normal cells form tight intra-connected colonies and therefore, NPs can be internalized mostly only at the edge of a growing colony, while in malignant cells, the cell cell and the cell matrix connection is disturbed and therefore, NPs can be internalized into any cell on the tissue culture plate (Gal et al. 2015).
