Exact(5)
Al-Afdal, Saladin's eldest son and emir of Damascus, was initially recognized by the younger sons as their overlord.
The disease was initially recognized by Russian scientists in the 1940s (3 ), and the virus was first isolated in the Democratic Republic of Congo some years later (4 ).
Diabetic cardiomyopathy was initially recognized by Rubler et al. [ 5] in diabetic patients, who exhibited defects in myocardial contraction and relaxation, and increased morbidity and mortality.
The receptor-binding cancer antigen expressed on SiSo cells (RCAS1) was initially recognized by the mouse monoclonal antibody, 22-1-1, which was raised by the immunization of mice with the human uterine cervical adenocarcinoma cell line SiSo [ 1].
E6 is best known for its ability to bind to p53 and induce its ubiquitin-dependent degradation [ 10, 11], whereas E7 was initially recognized by its ability to interact with members of the retinoblastoma protein family, namely pRb, p107 and p130 [ 12] and its capacity of enhancing their degradation [ 13].
Similar(55)
Alloantigens are often highly immunogenic, capable of evoking brisk, severe, and refractory allograft rejection, and are initially recognized by ≤10% of the recipient T-cell repertoire [49].
In this work, we attempt to add a component of flexible alignment in local variable regions which are initially recognized by rigid body superposition.
Microorganisms that invade a vertebrate host are initially recognized by the innate immune system through germline-encoded pattern-recognition receptors [1].
These splice-site elements are initially recognized by U1 snRNP, which binds at the 5' splice site, and by SF1/mBBP, U2AF65 and U2AF35, which bind cooperatively to the branchpoint sequence [3], [4], polypyrimidine tract [5], [6] and 3' splice-site AG dinucleotide [5], [7], [8], [9], respectively.
Our results show that all three forms were initially recognized by the anti-oligomer antibody, but AT3/182Δ and AT3Q24 gave an approximately constant signal over time unlike AT3Q55, whose signal progressively faded and completely disappeared at a 30-h incubation (Fig. 1B).
The N-MTS is initially recognized by a receptor in the outer membrane translocase (TOM) complex.
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