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Independence from insulin injections was initially achieved in about 80%% of patients at 1 year post-transplant and significant reduction in hypoglycaemia unawareness.
Chisholm et al summarised the key findings from the Edmonton study as follows: Independence from insulin injections was initially achieved in about 80%% of patients at 1 year post-transplant and significant reduction in hypoglycaemia unawareness.
With water vapor pretreatment, near complete CO2 removal was initially achieved and maintained for about 1 2 min at 50 °C with 2 s gas residence time, while without proper water vapor pretreatment CO2 removal abruptly decreased from the beginning.
Upon bioaugmentation and continuous addition of butane and dissolved oxygen and or hydrogen peroxide as sources of dissolved oxygen, about 70% removal of 1,1,1-TCA was initially achieved.
This was initially achieved by fitting one connecting rod inside the other at the lower end in a blade and fork arrangement; however, after cracking of the connecting rods was found during testing in 1931, the rod design was changed to an articulated type.
This was initially achieved through embryoid body (EB) formation in the presence of retinoic acid [12] or, alternatively, by co-culture of ES cells with stroma/conditioned medium [13], [14].
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Higher OH densities are initially achieved using Kr, but the Stark decelerator has to be operated at a higher phase angle and therefore lower stable phase-space volume in comparison to Xe.
Uniform and smooth hexagonal sheets are initially achieved for the first anion-exchange leading to nanowire-woven hexagons, followed by transformation of each nanowire to rough MCo2S4 nanotube via the second anion-exchange.
A concept of damage limitation, first introduced into general surgery in the military sphere by Rotondo, was adopted; now known as damage control [7, 8], it envisages a two-stage approach to serious multiple trauma or critical patients — emergency stabilisation is initially achieved through EF and followed with a second stage, 5 7 days later, of definitive internal osteosynthesis.
At a low nominal thickness, i.e., short deposition time, an amorphous (nominal) layer thickness of 15 nm is initially achieved.
In summary, this study showed that islet graft survival and adequate metabolic control can be markedly prolonged when optimal graft function is initially achieved and suggests that PGF has a preeminent influence on long-term islet transplantation outcome.
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