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Among the peptides synthesized and evaluated, a lead peptide (6a) with potent activity (IC50: 4.4 nM) was identified against the MDR769 HIV-1 protease.
However, no significant anti-leishmanial activity was identified against two different strains of L. donovani by the contents from generic Miltefos™ capsules within the concentration ranges tested.
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Hence, a range of frequency values have been identified against which a draft pad must be tested for fatigue response.
Proteins were identified against the B. pumilus entries from the RefSeq protein database available at NCBI, which was appended to an existing bacterial database.
In the most extreme case, antibodies whose combining sites are comprised of only two residues – tyrosine and serine – have been identified against several protein antigens.
Aptamers have been identified against various targets as a type of chemical or nucleic acid ligand by systematic evolution of ligands by exponential enrichment (SELEX) with high sensitivity and specificity.
On the other hand, 26 top scoring hits were identified against the ligandable region at the A1 ARF6 interface which showed strong hydrogen bonding interactions, including guanidines, phosphates, Leucopterin and Aristolochic acid VIa.
CTL responses were identified against three epitopes, containing positions E98D and R184K (Table 3).
However, no aptamers have previously been identified against E-selectin, despite its pivotal role in inflammation associated with multiple diseases.
Samples were identified against the 89 reference samples using the two threshold values described as well as the smallest interspecific distance to minimize false negatives.
In four distinct case-studies, evolutionary analysis of keyword frequency change through time is compared to a model of random copying used as the null hypothesis, such that selection may be identified against it.
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