Sentence examples for was however defective from inspiring English sources

Regulated cargo recruitment was, however, defective.

To investigate if the 4x595R mutant TIAM1 was however defective in ubiquitylation and degradation, expression of HA-tagged WT and 4x595R mutant TIAM1 were induced in MDCKII cells that were subsequently pretreated for 3 hr with MG132 and stimulated with HGF for 30 min.

They found that mice with T cell specific deletion of TRAF6 could generate robust CD8 effector T cell responses which were however defective in their ability to transit to memory CD8 T cell population.

This novel mutation was, however, shown to cause defective receptor shedding, and is associated with reduced levels of sTNFR1 (soluble TNFR1).

Mean and median EGFR intensity were, however, increased in tumours with defective vs intact MMR, but did not reach statistical significance (P=0.065).

However, defective shedding is variable between different TNFR1 mutants and different cell types and thus cannot explain all the clinical features of TRAPS [ 3].

However, defective CTSB maturation was also found in enriched lysosomal fractions.

However, defective epithelial differentiation was detected in the mutant based on the expression of keratin markers.

The D474N mutant, however, was not defective in its interaction with CYLD as revealed by yeast-two hybrid assays (Figure 4C).

Their speech being defective, however, it is evident that they had not learned to utilize this channel adequately.

When PDS is defective, however, it leads to Pendred syndrome, a rare disease that produces deafness at birth due to improper fetal development of the inner ear and accounts for 7%to10%0% of all congenital deafness.