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We found that p110α was highly detectable in the early malignant transformed human ovarian surface epithelium (Figure 2A and B).
In arthritic joints, AnxA1 and FPR2 expression was highly detectable within the synovial lining (FPR2) and tissue (AnxA1 and FPR2) (figure 2B).
RANKL produced by infiltrating active T cells and macrophages was highly detectable in the synovial tissues of subjects with active rheumatoid arthritis (RA) [ 2, 3].
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All metabolites were highly detectable (> 95%); levels below the limit of detection (LOD) were replaced with the LOD divided by the square root of 2 (Hornung and Reed 1990).
Out of 192 assayed microRNAs, 162 were highly detectable (with cycle threshold (CT) <35) in more than 75% of the samples and were chosen for further analysis.
It makes intuitive sense that stomach content analysis yielded a higher estimate, considering that cicadas exoskeleton are mostly indigestible to the mice but are highly detectable in the stomach.
In human, telomerase expression is principally restricted to highly proliferating cells (germ cells and progenitor/stem cells) in adults, whereas telomerase activity is expressed during human embryonic development [17] [19] and it is highly detectable in immortalized cells and many tumour cell tissues [20] [22].
As mentioned before, GFP-LC3 is highly detectable in migrating immature neurons in the rostral migratory stream in vivo.
Brase et al. confirmed that circulating miR-141 and miR-375 were highly detectable in serum from patients with an advanced disease, and their levels correlated with high-risk tumors (Gleason-score ≥8 or metastasis) [ 113].
8-isoprostane is formed in a non-enzymatic reaction between ROS and arachidonic acid and is advantageous because it is very specific to lipid oxidation, yet is not affected by dietary lipid intake, and is highly detectable in urine samples (Roberts and Morrow 2000).
This method was highly consistent with the detectable results of HCV antibody and HCV RNA of HCV patient serum samples (Table 3, Fig. 4B).
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