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Early in his career, he thought perhaps he could quietly come out once he was further up the ladder.
Our paths had not crossed in Washington; but it appeared that George Osborne was further up the plane, travelling – wait for it – in upper class.
The answer must be both, but what may have made a crucial difference was that Team New Zealand's boat was further up its design evolution ladder than Oracle's when the racing began.
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The process was further up-scaled to a 9 kg production in a continuous packed bed bioreactor.
Also, the mRNA expression of adipogenic differentiation markers including adioponectin and aP2 was induced along with the expression of ALP, a marker for OBs, by BMP-2, which was further up-regulated by TGF-β inhibition (Figure 2B).
In DB animals, IGFBP-4 expression was further up-regulated, whereas, Wnt3 and NeuroD1 expression declined.
The expression of the iNOS enzyme was increased upon LPS stimulation of macrophages and was further up-regulated upon incubation with 4T1CM followed by LPS.
BMP-induced expression of Col10a1 gene, a specific marker for hypertrophic chondrocytes, was further up-regulated dramatically, upon treatment with SB431542.
CD25 down regulation was only partial on BIM-/ Treg cells in the absence of cytokines, but was further up-regulated in the presence of cytokines (Fig. 4a, two lower panels).
Only PRPH was expressed at lower levels in ICM than in TE and 26 genes were down-regulated after MAPK inhibition and the expression of 16 genes was further up-regulated (Table 6).
As expected, the expression of the RPCs markers was further up-regulated compared with that of the RAB group, as shown by real-time PCR analysis after 5 days of differentiation in RAB medium (Fig. 1a).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com