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pH was determined as the most sensitive variable and was further optimized.
The cell performance was further optimized by designing nanocrystalline TiO2 films with a double-layer structure composed of a light-scattering layer and a transparent layer.
Finally, the favorable binding mode thus obtained was further optimized by a short time molecular dynamics simulation (∼5 ns).
As the acid pretreatment uses more environmentally friendly reagents, less glassware, lab space, and equipment, it was further optimized.
The structural model was further optimized by the implementation of the first pass effect of artesunate into dihydroartemisinin.
The DNA extraction protocol was further optimized by adding silicon carbide sharps for lysis of fungal cell wall which significantly enhanced extraction yields.
Log Po:w (=3.1) was further optimized through manual sensitivity analysis in the range of 3.0 4.0 to match predicted Vss (=1.49 l/kg) to reported Vss (=1.1 l/kg) and to improve Cmax prediction.
The top-scored compound was further optimized for improved binding.
This acceptor sequence was further optimized to a 15-AA acceptor peptide sequence (GLNDIFEAQKIEWHE) [236].
The synthesis was further optimized by increasing the organic/inorganic precursor ratios.
The concentration of formic acid was further optimized to be 0.04‰.
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