All the compounds of 19a 19h were found potent against all three cell lines and five compounds (19c, 19d, and 19f 19h) were found more potent against H1975 than gefitinib.
Several types of drugs such as heparin, ticlopidine, clopidogrel, plasminogen activator (t-PA), urokinase and streptokinase were explored as clot lysis agent but only few of them were found potent for clinical purposes [40]-[43] [40]-[43]
The compound 3i was found more potent for clot lysis among all synthesized compounds.
Bag et al. showed that a hot aqueous extract of T. chebula fruit was found to be potent against Staphylococcus aureus strains, whereas an ethanol extract was found to be more potent against Escherichia coli strains [ 18].
The molecule 5 that was prepared was found to be potent bacteria and fungus inhibitor.
For rest of the parameters, none of the sample culture was found to be potent.
Of total of fifty active extracts neither was found to be potent in MCF7 test, and only twenty presented moderate inhibiting activity.
An initial lead from a small parallel library was found to be potent and selective in biochemical assays.
Among the various fungi isolated, Penicillium sp. CFR303 was found to be potent with 66.5 ± 0.9% tannin degradation.
The presence of mineral particles along with the cellulosic fines was found to have potent inhibitory effects on enzyme hydrolysis.
