In the youngest embryos injected at the posterior margin (stage 8 9; stage 10 after culture; n = 4), all fluorescent cells were found internalized as a cluster of mesenchymal cells, close to the site of injection (Fig. 3C,D; supplementary material Table S1).
Moreover, translocation depends on other factors different from dimension, but especially the type of material and also nanoparticles as small as 5 nm of diameter was found not internalized in nucleus but remain in cytoplasm [ 51].
T. forsythia lacks the enzymatic machinery required for myo-inositol synthesis but was found to internalize inositol from the medium for the synthesis of both Tf GL1 and Tf GL2.
While 53.3 % of the total cellular activity was found to be internalized for [68Ga]pentixafor, only 17.5%% of the total cellular activity was internalized in the case of [68Ga]NOTA-pentixafor.
Approx. 6.7 logCFU was found to be internalized in case of S. Typhimurium isolate and approx. 7.4 logCFU was internalized in case of S. Typhi isolate (Table 4).
FPLC-purified R-III was found to be internalized into PSCs via caveolae-mediated endocytosis, and its efficient cellular uptake was also observed in HSCs and podocytes among several cell lines tested.
In support of the latter option, LFA-1 was found to be internalized in CHO cells and neutrophils (Fabbri et al., 2005; Fabbri et al., 1999).
In accordance with this, the ErbB3- and ErbB4-specific ligand Heregulin1β was found to be internalized less efficient and much slower than the EGFR-specific ligand EGF, supporting that ErbB3 and ErbB4 are not endocytosed as efficiently as EGFR (Baulida and Carpenter 1997; Waterman et al. 1998).
The intracellular behavior of the polyplexes was monitored by confocal laser scanning microscopy, and it was found that the polyplexes were internalized into HeLa cells very effectively.
In response to both, a change in the instructional system and psychotherapeutic treatment of PTSD, a massive decline in experienced violence and in the severity of PTSD-symptoms was found, whereas depressive symptoms and internalizing and externalizing problems exhibited little change.
