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Despite of the sequence similarity, jerdonobin-II was found devoid of plasminogen activating effect.
Imidazo[1,2-α]pyridine, the parent scaffold, was found devoid of affinity for the adenosine A1 and A2A receptors.
However, T. belerica (466.6 ± 23.69 mg/dL) was found devoid of any effect (p > 0.05) on TC levels.
L. stoechas extract up to a dose of 600 mg/kg was found devoid of any hypnotic effect in mice; however, animals were found to be dull, calm, and relaxed.
The ethyl acetate fraction of the crude extract of A. spinosus (As.EtAc) was found devoid of stimulant effect and exhibited concentration-dependent relaxant effect on spontaneous and high K+ (80 mM -induced contractions with EC50 values of 0.48 mM -induced-0.63, n = 4) and 0.27 mg/ml (0.19-0.38, n = 4), respecontractions
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Further, selected compounds 3e and 4c were found devoid of cardiotoxicity post evaluation on myocardial infarcted rats.
In contrast to common HCC the APC and CDH1 (E-cadherin) genes were found devoid of any DNA methylation in FLC, whereas the GSTπ1 gene showed comparable DNA methylation in tumor and surrounding tissue at a moderate level.
By contrast, in the crypt-villus transition compartment (Fig. 2B) and in villi (Fig. 2C), i.e. as soon as the process of cell division is stopped and the differentiation takes place, the nuclei, visualized by DAPI, were found devoid of Ki67 and of PrPc, which was visualized in the cytoplasm and in the lateral membranes of adjacent cells.
With respect to the animal host, the association is essential – no living vesicomyids have been found devoid of symbionts.
The ethanolic extract from C. pallida leaves showed mutagenic activity in the TA98 strain (-S9), whereas dichloromethane fraction and stigmasterol were found devoid of activity.
Surprisingly, compound 4o having (S -1-phenylethanamine waS -1-phenylethanamineof any cytotoxicity.
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