"Down the line a bit, these sites will evolve to the point where they'll include players that are far upstream, like providers of sawmill equipment," he said.
The transcription start site of the BMP-7 gene was found to be far upstream (764 bp) of the initiation ATG codon.
The third possibility is that the effects of Ot B on DAF-16 indirectly acted on proteins whose function is far upstream of the IIS signaling pathway, and simultaneously acted on protein in parallel to the IIS signaling pathway to regulate DAF-16.
Because dendritic compartments often are distant from the nucleus, transcriptional control may be far upstream of the local events that regulate outgrowth and branching.
The replication initiation protein is encoded on an unstable transcript with a weak promoter, PA, which is far upstream of PD, and protein C is encoded from transcripts that come from PB.
In human GK, the pancreatic exon 1 is located near the pancreatic (neuroendocrine) promoter, which is far upstream of the remainder of the coding region (exons 2 10) common to pancreatic and hepatic GK isoforms.
Because the qPCR returned a fold change of 0.5 when ZIC4, which is far upstream from exon 1 of PROS1, and when PRR15, which is on chromosome 7, were used for normalization, we conclude that the deletion in this family involves PROS1 and GPR15, including at least 20 confirmed genes in between.
However, Barré acknowledged that as an "upstream" link in the palm oil supply chain, L'Oréal was far removed from the communities affected at plantation level.
An irrelevant region (region 2), which was located far upstream of the transcriptional start site and contained no RARE sites, was selected as a negative control.
