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It was extensively shown that this can be achieved by employing CC concepts where relay nodes can act as RESs.
As such, impaired fat oxidation in the fasted state was extensively shown in obese insulin-resistant and type 2 diabetic individuals [ 27].
Although its important role for apoptosis induction by single drugs was extensively shown, the role of NOXA for drug combinations remains elusive so far.
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Chlamydia trachomatis, Mycoplasma spp., Neisseria gonorrhoeae and Treponema pallidum have been extensively shown to be associated with infertility, particularly because of endometrial and tubal inflammation.
Allergic asthma is characterized by a failure of immune tolerance and the development of pathologic responses to inhaled aeroallergens, and vitamin D has been extensively shown to support immune regulation.
Microglia have been extensively shown to phagocytose Aβ [8], [9], [32].
Nevertheless, Cry1A toxins used in transgenic plants have been extensively shown to be specific against target insects and safe to non-target organisms [2] [4].
LysoTracker is a fluorescent dye that has been extensively shown to partition to acidified compartments within a cell, e.g. lysosomes and endosomes [38], [39], [40], [41].
Our first aim was to determine if the increases in extracellular excitatory amino acid levels is mediated by a VRAC-like pathway, as has been extensively shown in vitro.
It has also been extensively shown that M-CSF, via its receptor c-fms, is a strong activator of PI-3 Kinase which in turn activates Akt [54], [55].
PfEMP1 proteins encoded by parasite var genes and expressed on the surface of iEs were extensively shown to mediate various binding activities hence representing an important target for antibodies associated with protective immunity against malaria.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com