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Upon testing the isolated fragments, we found that the kinase domain alone was excluded consistent with activity not being the key determinant of nuclear uptake, whereas the RCC1 domain did localize to the nucleus (Fig. 5E and F).
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Results for the adjusted analysis and per protocol analysis (n = 39 as cotinine was detected in the urine of 4 volunteers and one volunteer had unknown compliance status; moreover, 3 periods with unknown compliance or non-compliance were excluded) were consistent with the main analysis (Table 4).
The result of the corresponding per-protocol analysis, from which H pylori-positive patients were excluded, was consistent with the result of the ITT analysis.
The isolation by distance pattern was, however, nonsignificant when the population from Ploudaniel was excluded (r = 0.65, P = 0.164), consistent with the low differentiation among the easternmost populations sampled (Table 4, Fig. 3).
GHS was excluded from MCA in order to be consistent with IRT.
Patients missing heights, or with a height less than 152 cm or greater than 203 cm were excluded to be consistent with prior work [ 13], as were those with unknown or missing genders, weight below 40 kg or above 300 kg, oxygen saturation (SpO2) above 100% or with median values below 50%, and median tidal volumes below 3 mL per kg of PBW.
Although a secondary effect of miR-195 cannot be excluded, this result is consistent with biologically active MREs for miR-195 in the CDS of the elastin gene.
If Pluvianellidae are excluded, the supertree is consistent with the sister group relationship of Burhinidae and Chionidae.
Although the involvement of potential PCR artifacts cannot be excluded, our results is consistent with what was shown previously for species within the genus Leptographuim[ 52].
Although off target effect of shRNA cannot yet be excluded, our results are consistent with the notion that accumulation of DNA damage led to increased protein aggregates that can compromise DNA repair processes and increase DNA damage (Bae & Guan, 2011).
Accordingly, an additional sensitivity analysis was performed in which 13 such patients were excluded; results were highly consistent with the original findings (e.g., total cost was 2.2 times higher for patients with versus without prior relapse rather than 2.8 times higher).
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