Sentence examples for was engineered to target from inspiring English sources

FHV protein A was engineered to target the endoplasmic reticulum (ER) via a heterologous tobacco etch virus ER-targeting domain, and was expressed in cis or in trans relative to the replicating FHV RNA1.

An improved surface-immobilisation system was engineered to target heterologous proteins onto vegetative cells and spores of Bacillus thuringiensis plasmid-free recipient strain BMB171.

For example, a custom meganuclease was engineered to target an endogenous sequence in maize [ 34].

These vectors are engineered to target mucosal epithelium, so are ideal for targeted delivery aimed at preventing respiratory diseases.

NPs can be engineered to target distinct cellular components representing multiple pathways of immunity.

Particulate systems which can be engineered to target specifically certain cells or tissues are another promising alternative.

In this respect, zinc finger protein DNA-binding domains can be engineered to target virtually any gene.

Vesicular stomatitis virus (VSV) is normally relatively innocuous but can be engineered to target cancer cells or to stimulate immunity against diseases such as AIDS or influenza.

Liposomes may be engineered to target inflamed endothelium by mimicking ligand receptor interactions between leukocytes and cytokine-activated endothelial cells (ECs).

To our knowledge, this is the first report demonstrating that oncolytic MVs can be engineered to target the lumenal endothelial surface of newly formed blood vessels when administered intravenously in living animals.

Chimeric Antigen Receptor (CAR) T cells that have been engineered to target CD19 have shown great promise in patients with relapsed and refractory B cell acute lymphocytic leukemia with remission rates of 70 90%.