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In this work, surface functionalization was engineered to regulate the interactions between a PCM of polyethylene glycol (PEG) and internal/external surfaces of a support of SBA-15 and the crystallization/stabilization behavior of PEG, and yield desirable thermal properties of the PEG confined in SBA-15 channels.
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Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells.
Water-soluble fullerenes can be engineered to regulate activation of mast cells (MC) and control MC-driven diseases in vivo.
Artificial transcription factors based on zinc finger proteins are engineered to regulate a variety of genes relevant to regenerative medicine such as a zinc finger transcription factor is designed to regulate the gene for vascular endothelial growth factor (VEGF).
Synthetic riboswitches are engineered to regulate gene expression in response to a variety of non-endogenous small molecules, and a challenge to select this engineered response requires robust screening tools.
Because numerous natural protein and RNA modules involved in c-di-GMP sensing have been discovered, various output modules can be engineered to regulate diverse biological activities by NIRW light.
Previously, RXR was engineered to be regulated by LG335, a synthetic inactive analog of the compound LGD1069 (also known as bexarotene, trade name Targretin®) [ 23, 24].
A bladder cell line was engineered to express a doxycycline (dox) regulated shRNA against PSCA.
First, because the antisense RNA mechanism relies on RNA-RNA interactions, we show how the specificity of the natural system can be engineered to create variants that independently regulate multiple targets in the same cell.
Marijuana plants have been engineered to be more potent than they were 40 or 50 years ago and need to be regulated accordingly, he said.
Furthermore, DCs can be engineered to express co-stimulatory molecules and adhesion molecules or to down-regulate negative modulators, thereby increasing their T cell-activating ability.
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