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Ring B homolog of lithocholic acid (20) was efficiently synthesized.
The chalcone-like series 1a 1g was efficiently synthesized from Morita Baylis Hillman reaction (52 74% yields).
A lactam analogue of apratoxin A, named as amidapratoxin A, was efficiently synthesized over 22 linear steps in 2.1% overall yield for the first time.
The [N⋅⋅⋅I+⋅⋅⋅N] halogen-bonded hexameric capsule was efficiently synthesized from the isolobal metallosupramolecular Ag+ capsule by application of the [N⋅⋅⋅Ag+⋅⋅⋅N] → [N⋅⋅⋅I+⋅⋅⋅N] cation-exchange reaction.
The (Lys-Gly)5cyclo 75 82 MBP74 85 was efficiently synthesized by solid-phase synthesis and purified to a high degree, as confirmed by CE analysis in a low-pH (3.0) phosphate buffer and normal polarity.
2,3-Diamino-9,9-dioctylfluorene (DADOF), as a new multifunctional intermediate for π conjugated molecules, was efficiently synthesized via a seven-step procedure with an overall yield of 30%.
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Conclusion: The peptides were efficiently synthesized and the tested radiolabeling strategies showed successful results.
They can be efficiently synthesized and are extremely active against several diseases, including diabetes.
Novel ω-oxygenated vitamin K2 analogues were efficiently synthesized and their biological activities were evaluated.
The PU-H58-dimers 13a 15b were efficiently synthesized and their biological properties were evaluated.
Two series of novel pyrazolobenzothiazine-based hybrid compounds were efficiently synthesized starting from saccharin sodium salt.
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