Sentence examples for was effectively abrogated from inspiring English sources

When IL-23 was thus neutralized, IFN-γ production was effectively abrogated (Fig. 5B), even when exogenous IL-18 was added (data not shown).

AR-42-mediated apoptosis, as defined by annexin binding and processing of the caspase substrate polyADP ribose polymerase (PARP) to its 85 kDa form, was effectively abrogated by Z-VAD-fmk.

As shown in Fig. 7A & B, icaritin induced cell apoptosis was effectively abrogated by U0126, a potent inhibitor of MEK1/2, but the p38 inhibitor SB203580 and JNK inhibitor SP600125 had no effect, suggesting that the activation of ERK1/2 signaling is involved the icaritin-induced apoptosis.

BRCA1 expression was effectively abrogated, as shown in Western blot analyses (Fig 1A).

Most interestingly, despite the fact that p-EGFR[Y1068 p-EGFR[Y1068nificantly inhibited under the dual SU11274/erlotinib combinatorial treatment in H1975 cells, p-ERBB3[Y1289] activation was effectively abrogated onot under thisignificantlytory strategy.

Importantly, the binding between the protein and the labeled probe was effectively abrogated by specific unlabeled probe but not by non-specific probe which contains mutations in the core SOX binding sequence.

As shown in Fig. 5A, treatment with E2 induced cyclin D1 and cdk4 expression in Ishikawa/V cells but not in Ishikawa/RNAiER36 cells, which could be effectively abrogated by the PKCδ inhibitor rottlerin and MEK inhibitor U0126 (Fig. 5B).

As shown in Fig. 5A, treatment with E2 or tamoxifen induced c-Myc expression in Hec1A/V cells but not in Hec1A/RNAi ER-α36 cells, which could be effectively abrogated by the MEK inhibitor U0126 (Fig. 5B) and PI3K inhibitor LY294002 (Fig. 5C).

Furthermore, these expansions were effectively abrogated when cells were treated with a combination of NOTCH1 and NOTCH2 blocking antibodies, suggesting that they were at least partially NOTCH mediated.

Induction of ICER links oxidative stress to beta cell failure caused by oxidised LDL and can be effectively abrogated by antioxidant treatment.

Indeed, we show that JNK is the sole MAPK whose activation by Cr VI) is effectively abrogated in Map2k7 ES cells.