Sentence examples for was discovered to bind from inspiring English sources

Thiocyanate was discovered to bind with high affinity in the third anion-binding site at the bottom of the barrel.

Furthermore, via random mutagenesis, a hVDR mutant, H305F/H397Y, was discovered to bind a novel small molecule, cholecalciferol, a precursor in the 1α,25-dihydroxyvitamin D3 biosynthetic pathway, which does not activate wild-type hVDR.

JNK, a c-Jun NH2-terminal kinase, was discovered to bind to the c-Jun transactivation domain and phosphorylate Ser-63, Ser-73 and some secondary sites (Devary et al, 1991; Hibi et al, 1993).

A transformative insight into glycan-recognition by T cells occurred when zwitterionic polysaccharides were discovered to bind to and be presented by MHCII to CD4+ T cells.

A novel series of benzoazepin-2-ones were designed and synthesized targeting the PIF pocket of AGC protein kinases, among which a series of thioether-linked benzoazepin-2-ones were discovered to bind to the PIF pocket of 3-phosphoinositide-dependent kinase-1 (PDK1), and to displace the PIF peptide with an EC50 values in the lower micromolar range.

More recently bcl-2 has subsequently been discovered to bind to, and suppress activation of the NLRP1 inflammasome, inhibiting release of IL-1 β in response to the NLRP1-activating ligand muramyl dipeptide, and also blocks the activation of the NLRP3 inflammasome in response to apoptotic stimuli in mouse macrophages.

Recently, Legionella pneumophila proteins were discovered to bind to PtdIns(4 P during host cell infection, and all three proteins namely SdcA Weberr et al, 2006), SidC (Ragaz et al, 2008) and SidM (Brombacher et al, 2009)—possess largely helical domains that suggest unique functions.

The amount of water bound to the gel was estimated and was discovered to vary depending on the ratio of sodium polyacrylate to polyacrylic acid and the temperature.

DMMTAV has also been discovered to be bound to rat hemoglobin, suggesting the possibility for pentavalent As interaction with sulfhydryls on proteins and peptides.

Since 1950, and particularly since 1960, several ionically bound compounds have been discovered to be ferromagnetic.

16 High-mobility group box 1 (HMGB-1) was recently discovered to bind the FG cleft in the immunoglobulin variable region of Tim-3 within DC endosomes.