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We excluded images with patchy staining because it was difficult to outline the iERM edges.
As it was difficult to outline the cells in BAT because of the accumulation of lipid in the cytoplasm, lipid area in BAT was quantified using MetaMorph Imaging Software.
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An evidence-based management plan with follow-up evaluations is difficult to outline because of the rarity of these tumors.
Thus, although the courts recognize a parody defense, the precise contours of such a defense are difficult to outline with any precision.
The coordinates of the points on the cellular outline were extracted manually to obtain a smooth outline for each image extending from the bottom to the top of the cell until the outline was difficult to identify due to the lack of staining in the top region.
It was difficult to discern more than an outline of each amplified aria amid the sirens, chatter and construction noise.
It was difficult to perceive much more than the simplest outlines of organs, and yet, quantitative measurements were already taking place.
It was difficult to focus on her; the sun silhouetted her in shadow, causing her outline to quiver and fade.
It was difficult to say.
It was difficult to judge.
That was difficult to swallow.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com