Sentence examples for was difficult to formulate from inspiring English sources

Thanks to the architecture of the optimiser, a multi-objective gradient-based optimisation, which was difficult to formulate, has been proposed.

These initial biological results suggested that subtle structural changes to the phenyl and acetamide bond of C-pseudonucleosides could have a significant effect on T cell proliferation bias, although it was difficult to formulate a rigorous structure-activity relationship based on the observed activities.

Another limitation of the tool is that it was difficult to formulate clear-cut criteria to demarcate high and low quality.

Participants in focus group 2 stated that it was difficult to formulate goals due to the uncertainty of the care process and the disappointments of the patients when goals were not reached.

β-carotene was used as a poorly water-soluble model substance that is difficult to formulate with conventional solid dispersion formulations.

It is difficult to formulate such a plan at this stage because the internal policy debate is still ongoing.

It did not take Arthur long to discover that it is difficult to formulate a useful model in conventional mathematical terms.

Intelligibility varies so much with the speaker and the hearer, however, that it is difficult to formulate firm criteria on that basis.

Most invitees understand that guest lists are difficult to formulate, and that budgets, venues and large families can force tough choices.

It is difficult to formulate a distinct definition for each of these terms, because their use largely overlaps in the literature despite individual preferences.

Without adequate data on the nature and extent of the problem it is difficult to formulate a policy to foster a culture of integrity that limits and discourages deviant behaviour.