Exact(1)
The deletion mutant T1223del was correctly transported to the cis-Golgi apparatus and showed co-localization with GM130 (Fig. 4).
Similar(58)
This study revealed four distinct loss-of-function mechanisms for the mutant hNav1.5 channels (Fig. 7): First, mutants R878C and G1408R were correctly transported to the plasma membrane, but did not form functional channels, suggesting a complete gating/permeation defect.
The mutants T644M and T1223del that were correctly transported and proteolytically cleaved into mature α- and β-subunits exhibited 50 and 85% of GlcNAc-1-phosphotransferase activity, respectively, of the WT enzyme.
To this end, it is noteworthy that a PEXEL containing RESA-GFP chimera was only correctly transported to its correct sub-cellular location when expressed under control of its endogenous promoter.
Even for wnt8a, while we observe a slight lag in a minority of M ybx1 sg8 deletion mutant embryos, wnt8a RNA does in fact get transported and is correctly localized both to the blastoderm and asymmetrically to the vegetal cortex (black arrowheads and arrow in revised Figure 4 figure supplement 1A), by the 4-cell stage in all mutant embryos.
This indicates that, in L. lactis, the produced protein is correctly folded and able to transport radioactive ATP into cells with the similar mechanism observed in chloroplasts, its original organelle.
Moreover, the role of transport should be correctly conceived in an economic and timely manner rather than in purely geographic terms.
Many pathophysiological aspects of the disease model were correctly recognized by the GO terms phototransduction, ion transport, apoptosis regulation and cone development.
Raydose uses CT units to determine attenuation coefficients for radiation transport; therefore, perturbation effects of local heterogeneities (e.g., PMMA phantom walls) are correctly accounted for.
"We are correctly positioned".
Has it been correctly applied?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com