Sentence examples for was cmax from inspiring English sources

It has been suggested that the onset of the effect of triptans is related to the systemic drug-transfer rate[10], thus parameters expressing drug transfer and binding rates (A cp, A Ф 1B, A Ф 1D ) were calculated by using (Eq. 3, 4, 5), where the maximum plasma concentration was Cmax, and the time to maximum concentration Tmax and the maximum occupancy were Фmax1B and Фmax1D, respectively.

The only exception was Cmax, for which the upper limit of the 90% CI (point estimate 1.2255 with a 90% CI: 0.9983, 1.5045) extended slightly above the pre-defined no relevant effect interval.

Hence, the only reported parameters are Cmax, Tmax, Clast, and tlast, and the only calculated parameter was AUC0 24 (Table 4).

The pharmacokinetic parameters calculated were Cmax, tmax, AUC0-t, AUC0-last, and the metabolite to parent AUC0-t ratio.

Primary PK parameters were Cmax and area under the curve (AUC)(0 12) for Sb, and Cmax and AUC(0 24) for TMZ.

At this dose, the pharmacokinetic end points were reached, that is, Cmax and AUC∞ were comparable to those obtained in mice under protecting conditions.

PK parameters assessed were Cmax, Tmax, area under the curve (AUC) Last, and AUC0-inf., systemic clearance (Cl), volume of distribution (Vdβ) and elimination half-life (t1/2_lambda_z).

Figure 4 displays typical features for formulations where the surfactant concentration before dilution was at cmax.

Our hypothesis was that Cmax and bioavailability of phenobarbital differ between the two pharmaceutical formulations, at least in individual dogs.

The EMA specifies the parameters as being AUC, Cmax, and Tmax (EMA 2010).

Thus the main, and clinically most important, differences between the groups were in Cmax and AUC.