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The current report is concordant with the notion that activation of Akt upon mTOR inhibition is a mechanism of resistance to these agents as the HEP2 cell line in which this phenomenon was observed was clearly resistant.
Yet, LAP-mouse PICH was clearly resistant to PICH-1 siRNA treatment; in fact, LAP-mouse PICH showed enhanced expression upon depletion of endogenous human PICH, suggesting the existence of a feedback mechanism controlling total PICH protein levels (Fig. 3c).
Although virus recovered at passage 4 from one of five mice treated with VCV (14-P4) was clearly resistant in the PRA (IC50s 8.3 and 9.5 for PCV and ACV, respectively), the preceding and the subsequent isolates were sensitive according to the criteria for defining resistance.
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On Friday, the interior and justice ministers were clearly resistant to the idea of handing over any major intelligence function to a European government.
But conservatives amended that draft in subcommittee today to say that the role of the federal government in education "must be progressively limited," and were clearly resistant to much of the detailed education agenda put forward by the Texas governor.
However, the tumours were collected at autopsy and were clearly resistant, very large, and actively growing on treatment with VN/124-1 VN/124-1
Healthy C. micronesica trees are clearly resistant of tropical cyclone disturbance, especially in comparison to sympatric native and exotic taxa.
Our mutants were clearly resistant to age-related obesity, notably exhibiting elevated insulin sensitivity, which reminds the metabolic features of some long-lived mutant mouse strains (Bartke & Westbrook, 2012).
Thus, blood type B15/B15 was clearly more resistant, but the resistance appeared to be fully recessive, as survival of the B2/B15 heterozygote was virtually identical to that of the B2/B2 homozygote.
This corresponds almost exactly to the calculated degree of map expansion in this population based on unpublished data (J.E. Fulton and E. Lipkin pers. comm).. MHC type B15/B15 was clearly more resistant than B2/B2 and B2/B15, but the resistance appeared to be fully recessive, as the heterozygote was virtually identical to the B2/B2 homozygote.
With both plastics, the nickel insert with thin film of molybdenum nitride was clearly more resistant to contamination than the uncoated insert.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com