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The Δ Fmax for lipid A quenching also increased 2-fold when daunorubicin was bound first, indicating that conformational changes take place at the lipid A binding site when the drug-binding site is occupied.
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Meanwhile, Fossett and the crew of his 125-foot catamaran, PlayStation, are bound first for the Caribbean island of Antigua, and then Miami.
The DNA strand-exchange reactions promoted by the RecA proteins from all other bacteria studied to date are ordered such that the single-stranded DNA is bound first, followed by the double-stranded DNA.
When a PEP-promoter is bound, first the initiation abort, then elongation are modeled.
Interestingly, a comparable reduction in lipid A binding affinity (4- to 7-fold) is observed when daunorubicin is bound first, suggesting that similar structural rearrangements may be taking place.
In the case of H2A.Z and H3K27me3 dual asymmetry, we confirmed that the frequency of 3C5 DSCs with H3K27me3 asymmetry was similar when the anti-H3K27me3 antibodies were used alone (25%) or in combination with anti-H2A.Z antibodies, whether they were bound first (as routinely; See Materials and Methods; 33%) or second in the procedure (26%).
The 3′-amino group in the first sugar was replaced by an hydroxyl group, and the second sugar residue was bound to the first sugar via an α (1 4) linkage.
Her own view of these achievements was modest: "Some woman was bound to be first.
His brother, running newspapers, was bound to be second-guessed by his father; James had a much wider berth.
Rather, for N3, 3- p-tolyl)allyl-Neu5Ac2en was bound to the second sialic acid binding site between two adjacent NA molecules (Fig. 2I and 2J).
A supplement appeared in 1845; it was bound into the third volume of the rare "Imperial Octavo" edition of 1845, of which only 50 copies were printed.
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