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Differential expression was assessed use a moderated t -test for each miRNA using both mouse and human data.
The influence of the following variables on clinical outcome was assessed: use of amines; fluid balance (FB) in the perioperative period (PER); time of ECC, anoxia, and mechanical ventilation (MVT); ICU length of stay (ICULOS); hospital length of stay (HLOS); complications of the procedure; and death.
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Subjective sleepiness was assessed using the Stanford Sleepiness Scale.
Sleep was assessed using polysomnography.
Severity was assessed using the SAPSII [16].
Clinical outcome was assessed using different questionnaires.
Linearity was assessed using a residual plot.
It was assessed using the kappa test.
Oxidative stress was assessed using DHE.
Heterogeneity was assessed using the previous method.
Systemic oxygenation was assessed using pulse oximetry.
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