The 4 h culture supernatant of S1444 was already more potent at killing bovine neutrophils as compared to S1449 and S1463 (Fig. 3c) (p ≤ 0.05, Supplementary Fig. S1).
Scott Stoermer, a spokesman for the League of Conservation Voters, said that shifting cleanup costs from industry to taxpayers was already a potent political issue in certain Congressional districts and was likely to become more so in the current atmosphere of corporate scandals.
"I don't think you need to use gene therapy to develop a biological weapon," Varmus said, pointing out that existing organisms--anthrax and smallpox, for example--are already potent weapons.
The orchestra was already a singular, potent institution when Borda arrived: her contribution was to understand its nature and move it forward.
Furthermore, a Dct-dependent intermediate of the melanin synthesis was already established as a potent hydroxyl radical-scavenging agent [ 13], indicating a possible role for melanocytes in murine and human vessels in the regulation of antioxidation processes, too.
Carnegie is already a potent force on the classical music scene, staging festivals, anointing composers and musicians in residence and showcasing soloists, chamber groups and orchestras in the concerts that it presents.
And that's with a four-cylinder engine that's already more potent than the Jetta's.
On the other hand, in the DAD cohort more than 80% of the patients at the time of enrollment (1999 2001) were already receiving potent ART for a median of almost 2 years, with most individuals having undetectable HIV-1 RNA viral loads and a state of low cellular activation.
We speculate that Tregs may have a maximal suppressive activity; IL-2/anti-IL-2 mAb treatment may not be able to further improve Treg's inhibitory activity when Tregs were already very potent during the stimulation phase.
