Suggestions(2)
Exact(3)
The assessor was adequately blinded in six trials [13, 14, 16, 19, 20, 22].
In half of the studies it was uncertain whether or not outcome assessment was adequately blinded.
Firstly, our sample size was larger than any previous trial and was adequately blinded, unlike Savino and colleagues' trial.
Similar(55)
Blinding - We considered whether participants, care providers and outcome assessors were adequately blinded as to who received the intervention and who received placebo.
Patients, care providers, and outcome assessors were adequately blinded in approximately one-fifth of the reports.
Another limitation that each assigned treatment was unable to be adequately blinded to the patients, possibly resulted in bias.
It seems unlikely that many were adequately blinded, as, in trials for people with schizophrenia, just over one fifth have adequate descriptions [ 9].
If subjects in the AC group reported that stimulation intensity was indeed reduced on demand (regardless of exact sensation intensity), these subjects were considered to be adequately blinded, and their data were used in subsequent analysis.
For subjects assigned to the active coping condition (n = 31), 18 subjects were deemed to be adequately blinded and, thus, included in the analysis; 7 subjects pressed the button only once (i.e. indeterminate blinding) in AC group, and among the rest (n = 24) who pressed the button twice, 6 were found to be unblended.
Intra-/inter-rater reliability was properly assessed, examiners were adequately blind regarding clinical information, and the two groups were comparable with regard to the most relevant confounding variables.
Finally, we were only able to investigate neurological outcome at the time of hospital discharge, and this variable was not adequately blinded.
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Justyna Jupowicz-Kozak
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