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An adjusted analysis was done where the model was additionally adjusted for age, gender, occupation, and the baseline value of the metabolite.
The multivariate-adjusted model of age of starting smoking among current-smokers was additionally adjusted for th4e amount of smoking.
All the echocardiographic findings were adjusted to BSA−0.5, while left ventricle mass (LVM) was additionally adjusted to BSA−1.5.
A further sensitivity analysis was calculated where Model 1 was additionally adjusted for hemoglobin.
The second was additionally adjusted for variables identified as being associated with both CRC and energy balance from previous literature.
Two further sensitivity analyses were calculated where the extended model was additionally adjusted for current smoking and phosphorus levels, respectively.
The p-value of the significant association of periconceptional folic acid use and IGF2 DMR methylation was additionally adjusted for maternal education.
The p-value for the significant association between IGF2 DMR methylation and birth weight was additionally adjusted for periconceptional folic acid use and gestational age at delivery.
The second model (Model 2) was additionally adjusted for albumin, C-reactive protein, current smoking status, native fistula and echocardiographic data (ejection fraction ≤60% versus >60%).
HbA1c was additionally adjusted for diabetes duration.
Model 2 was additionally adjusted for BMI.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com