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The outcomes of genetic analysis at 11 microsatellite loci and mtDNA indicated that population recovery was achieved predominantly by residual animals: recovery populations were genetically more similar to their respective pre-treatment population than near neighbours; assignment tests detected few immigrants; there was no influx of new immigrant alleles and haplotypes.
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Production of these often complex transgenic proteins is achieved predominantly in mammalian cell lines but the process is hampered by low yields and unstable expression.
In S. cerevisiae regulation of cell cycle progression is achieved predominantly during a narrow interval in the late G1 phase known as START (Pringle and Hartwell, 1981).
NST in mice is achieved predominantly through activation of uncoupling protein 1 (UCP1), which requires sympathetic release of NE and activation of β3-adrenergic receptors in brown adipose tissue [8], [19].
Thus, yield increases have been achieved predominantly by expansion of cultivated area and not through yield enhancement.
Interestingly, the inactivation of ARID1A in clear cell and endometrioid carcinomas also in breast cancer cell lines (Mamo et al, 2012) appears to be achieved predominantly through mutations, with little or no evidence of epigenetic inactivation (Wiegand et al, 2010).
The structure, together with RNA binding assays, shows that the selection of 5′-splice site nucleotides by U1 snRNP is achieved predominantly through basepairing with U1 snRNA whilst U1-C fine-tunes relative affinities of mismatched 5′-splice sites.
In large muscles such as the quadriceps, force increments are achieved predominantly through recruitment of progressively larger MUs, with a smaller contribution from increases in firing rate at higher intensities [ 2].
The feedback regulation of isoprenoid biosynthesis by cholesterol is achieved predominantly through the repression of transcription of genes that govern the synthesis of cholesterol, such as HMG-CoA reductase and HMG-CoA synthase [ 51].
On average, a reduction of AHP of 1.3°/mm was achieved by predominantly performing combined horizontal recess-resect surgery in the intact eye.
An impressive 3.4% absolute reduction in intensive care unit mortality was achieved in predominantly surgical patients managed with insulin to achieve a blood glucose level of 4.0 6.0 mmol/l (80 110 mg/dl) as compared with a 'control' target range of 10.0 11.1 mmol/l (180 200 mg/dl).
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