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In addition, this was a monocentric study.
First, this was a monocentric study.
As in most other publications, our investigation was a monocentric study.
Second, it was a monocentric study including only ICU patients admitted for meningitis, and so extrapolating the results to a general ICU population remains speculative.
Although it was a monocentric study, our results seem both clinically and statistically meaningful, as this study employed a randomised design and few patients were lost to follow-up.
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It is a monocentric study and results have to be confirmed in a larger population.
Methods: This is a monocentric study from January 2006 to December 2014, conducted in universitary hospital in Grenoble, France.
It is a monocentric study conducted in an ICU located in a hospital with departments specialized in oncology, hematology and hepatology.
Second, this is a monocentric study, so it is possible that our local protocol including VAP prevention bundle, diagnosis strategies and therapeutic management could influence the occurrence and the prognostic impact of the disease.
It is a monocentric study and results need to be confirmed in a larger population.
The trial will be carried out at Heidelberger Ionenstrahl-Therapie centre (HIT) and is a monocentric study.
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