The remodeling of root architecture is a major developmental response of plants to phosphate (Pi) deficiency and is thought to enhance a plant's ability to forage for the available Pi in topsoil.
This process, referred as CD4 and CD8 commitment, is a major developmental process after positive and negative selection.
The transition from a vegetative to a reproductive phase (i.e., flowering) is a major developmental switch in the plant life cycle that must be properly timed to ensure maximal reproductive success.
The WNT signalling pathway is a major developmental pathway that is involved in cell fate, differentiation and proliferation.
Resolution of apnea and establishment of a normal respiratory pattern is a major developmental milestone for many premature infants.
Pregnancy and the transition to parenthood is a major developmental period with important implications for parents, for the infant-parent relationship and the infant's development.
DOI: http://dx.doi.org/10.7554/eLife.01567.011 Secondary growth is a major developmental process in dicotyledons, including herbaceaous plants such as Arabidopsis (Chaffey et al., 2002; Sibout et al., 2008; Elo et al., 2009); however, it is comparatively an under-researched trait.
Flowering is a major developmental transition in the life-history of plants, and the genetic manipulation of flowering time has been crucial in the domestication and spread of cereal grasses such as wheat, rice, and maize.
Hedgehog (Hh) signaling pathway is a major developmental signaling pathway that governs embryonic development and adult tissue homeostasis, and its deregulation leads to birth defects and cancers including medulloblastoma (MB).
We hypothesize that there is a major developmental switch in gene expression occurring during late fetal development which is associated with tertiary myotube formation and changes in the oxidative status of muscle in preparation for the new physiological demands on the muscle in the postnatal environment.
