The low resolution of this crystal structure (3.6 Å) and poor data quality did not warrant refinement past the initial molecular replacement solution.
However, the data analysis showed that the categories of Judgement and Appreciation warranted further refinements, which are discussed below.
Currently, we do not have sufficient dose response clinical data available in the literature to warrant model refinement based on the data.
Identification mechanisms for eating episodes and image deletion functioned, but warranted additional design refinement to enhance user-friendliness and maximal use of the images.
Given the critical involvement of cortical functioning in learning and memory, Golgi analyses of cortical cell morphology is warranted; however, further refinement of a possible localized cortical target would significantly improve the ability to detect biologically meaningful changes.
The multifaceted tailored intervention appears to be feasible but further refinement is warranted prior to testing the effectiveness of the approach on a larger scale.
If the results of IPW/MI and MI/MI are very different, further exploration would be warranted, possibly leading to refinement of the imputation model.
Representatives of the Bay Bridge, Golden Gate Bridge and the California Highway Patrol said security was as tight as it had ever been and would remain that way, with refinements as warranted.
In light of these intriguing results, we re-examined the Hebrew translations in order to ascertain where refinements are warranted.
Over recent years, several genetic methods have been developed to achieve mosaicism in zebrafish, but despite their advances, limitations remain and different approaches and further refinements are warranted.
Job projections would probably rise slightly if we specifically allocated $50 million per year for administration, technical assistance and workforce training because these labor intensive activities result in a higher number of jobs per million dollars of investment.9 However, there is insufficient information to warrant this additional refinement of our estimates.
