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Further preclinical studies on PPAR α agonists are warranted for the development of a clinically applicable therapeutic strategy against ALF.
To improve the efficacy of tumour vaccines and decline immune escape, further identification of novel CT antigens is warranted for the development of applicable polyvalent tumour vaccines.
However, inhibitors of NMDA receptors largely failed in clinical studies and, therefore, novel strategies controlling [Ca2+]i homeostasis are warranted for the development of effective therapies of neurological disorders associated with excessive NMDA receptor stimulation.
43 44 Given the overlap between these barriers and those that GPs encounter in multimorbidity, it is likely that special attention is warranted for the development of models of decision-making for multimorbid patients.
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Our results show that rational design of antigens is warranted for further development of malaria vaccines.
It seems that further in-depth pre-clinical animal studies and, ultimately, clinical trials on BD is warranted for development of this chemical into anti-cancer pharmaceutical.
Validation for the inherently functional definition of AZFc has been warranted by the development of Y microdeletion screening programmes in the male population.
Further study on TH-GM cells including their physiological functions is warranted for targeting these cells for the development of therapeutic interventions for human inflammatory diseases such as MS. It is interesting to see that STAT5-regulated TH-GM cells are not required in a T-cell transfer model of colitis.
Large-scale longitudinal studies are warranted for evaluating the potential of PTMA overexpression to identify patients with oral lesions at high risk of cancer development.
This indicates that an extensive search for CTL epitopes in various clades is warranted to facilitate the development of globally effective CTL vaccines.
Prophylactic treatment seems warranted to prevent the development of permanent ocular palsies seen in OD.
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CEO of Professional Science Editing for Scientists @ prosciediting.com