Sentence examples similar to warranted amplification from inspiring English sources

These data are in agreement with the manufacturer's instructions according to which at least 1 ng (optimum 10 ng) of purified DNA is to be used for the reaction to warrant minimum amplification bias.

Intensity and pattern of membrane staining seen in at least 10% of cells was scored: 1+ = non-amplified, 3+ = gene amplification, and 2+ = equivocal result and warranted further investigation of amplification status using an INFORM HER2/neu DNA probe with a silver in situ hybridisation (SISH) technique according to the manufacturers instructions (Roche Diagnostics).

On the other hand, under physiological conditions, PTP1B modulates insulin signaling pathway in a reversible feedback manner, which warrants the orderly amplification and attenuation of insulin signal.

A single-nucleotide difference between two otherwise identical DNAs is the best competition structure that warrants the equal amplification efficiency of these dimorphic DNAs in the PCR.

Based on our results, further studies analyzing the prognostic impact of EGFR amplification in a large cohort of MBCs are warranted.

Further studies investigating the mechanisms that lead to a survival advantage in cancer cells harbouring amplification and overexpression of PLEKHF1 and POP4 are warranted.

Because most metaplastic breast carcinomas overexpress EGFR without gene amplification, further studies to evaluate EGFR activating mutations are warranted.

Biologically, the striking issue is why progression to invasive disease would imply loss of HER2 amplification, which warrants further attention.

Further investigation of a role for FGFR1 amplification in predicting chemoresistance and a potential mechanism for this is, therefore, warranted.

Future studies designed to assess the predictive value of HER2 amplification and overexpression and response to trastuzumab or other anti-HER2 agents in OCCCs are warranted.

Caution is warranted for use of this locus in neoplasms such as adenoid cystic carcinomas that have a high rate of TBP amplification or deletion.