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Forgotten before the nightcap, the principal players not prominent enough to warrant sustained attention".
Pharmacokinetic studies showed that (i) the type of hepatic pathology has a major impact on the kinetics of silymarin, (ii) doses above 700 mg tid may reach much higher blood levels than predicted from linear dose/blood levels at lower doses and (iii) the short half-life of silymarin indicates that at least 3 daily intakes are needed to warrant sustained effective blood levels.
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Although an encouraging flattening in the increasing trend of ADR-related admissions was found around 1997, the incidence is still rising, which warrants sustained attention to this problem.
The commander, Adm. William H. McRaven, said "there was nothing unusual about this mission" to warrant the sustained criticism heard from some retired commandos and military analysts, who have questioned how the operation was planned and carried out and whether it was an appropriate use of the vaunted Navy Seals.
The increased prevalence of obesity in present day society and the current view of adipose tissue as one of the most critical regulators of energy homeostasis and metabolism have warranted a sustained interest in studying the mechanisms controlling its formation.
Booster sessions seemed warranted to sustain long-term effects (4).
With a lethality rate of approximately 60% in reported laboratory-confirmed human H5N1 cases (10), maximum preparedness is warranted in case sustained human-to-human transmission were to evolve.
He realized that it was his death warrant, and from that time sustained work became impossible.
An AECOPD is defined as 'an acute worsening of the patient's condition from the stable state, which is sustained and may warrant the patient to seek additional treatment' [ 23].
AECOPD was defined as 'an acute worsening of the patient's condition from a stable state of COPD that is sustained and may warrant the patient to seek additional treatment'.
This issue was also raised by colleagues van der Brand et al., who concluded that the high percentage of patients that had sustained a fracture warrants radiography in all patients with wrist trauma [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com