This "idle" state is not part of the ictal process itself but allows vulnerable regions to generate epileptic discharges; electrically, it reflects a long-range de-synchronization between cortical sources which takes place few seconds before seizure onset.
Murthy (2006) found that open ground storey buildings were highly vulnerable to shear generated during strong earthquakes and those were relatively flexible in the ground storey.
We believe that during mekk-3 knock-down, requirement for xenobiotic detoxification is so enhanced that mutations in key proteins in this pathway may make the worms vulnerable to internally generated toxins and result in suppression of lifespan.
Ziadeh, who produces professional upcycled furniture through his company, Ziadat for Recycling, has been approached by organisations including UNHCR and UNDP to teach refugees and vulnerable Jordanians how to generate an income by refashioning rubbish.
We were also limited to generating recommendations for those who were provincially insured, which represents a more vulnerable segment of the population.
We are trapped in a vicious cycle: we will need to grow 50% more food by 2050 to feed 9 billion people but agriculture, which is paradoxically vulnerable to climate change, generates 25% of heat-trapping greenhouse gas emissions that lead to climate change.
The investors also contend that because real estate taxes are not being paid on many loans in the portfolio, a lot of the properties now carry tax liens, which make them vulnerable to foreclosure and generate increased fees related to default.
Due to the high amount of oxygen consumption, high levels of unsaturated fatty acids, and the relative lack of antioxidant enzymes in the brain, nerve cells are particularly vulnerable to free radicals generated by oxidative stress, which results in lipid peroxidation and the damages membrane structure.
Vulnerable nodes also attempt to generate their own repairs.
Proteolytic cleavage to generate vulnerable precursors, such as amyloid-β peptide (Aβ) production via β and γ secretases in Alzheimer's Disease (AD), is one such trigger, but the proteolytic removal of these fragments is also aetiologically important.
