Sentence examples for vulnerable to cell from inspiring English sources
Therefore, the decreases in Nurr1 mRNA and protein levels in midbrain after METH challenges both in saline- or METH-pretreated animals are disconcerting because they might render DA neurons more vulnerable to cell death.
Interestingly, hippocampal neurons are less vulnerable to cell death induced by loss of presenilins, whereas lateral cortical neurons are particularly vulnerable, suggesting brain subregion specificity for presenilin-dependent neuronal survival.
Membralin mutations or deficiency in mouse models induces ER stress, rendering neurons more vulnerable to cell death.
Late OPCs also were found to be vulnerable to cell death in other models of neonatal white matter injury (Vottier et al., 2011; Falahati et al., 2013).
Furthermore, activation of AMPK by AICAR could also make BT474 cells more vulnerable to cell death by 3-BrOP (Additional file 7: Figure S6A).
In neurodegenerative disorders associated with primary or secondary mitochondrial defects such as Huntington's disease (HD), cells of the striatum are particularly vulnerable to cell death, although the mechanisms by which this cell death is induced are unclear.
Given that MHC-I also constitute the chief NK cell inhibitory ligands, their downregulation has the potential to render infected cells vulnerable to NK cell attack.
It was proposed that the binding of angiostatin to plasma membrane-localized ATP synthase may disrupt production of ATP and render endothelial cells more vulnerable to irreversible cell damage [ 37].
Accordingly, poly(ADP-ribose) polymerase (PARP) cleavage was detected in 38 × or 72 × repeat transfected SH-SY5Y cells, but not in HEK293 cells, suggesting that neuronal cells may be more vulnerable to apoptotic cell death triggered by G4C2 RNA foci.
These combined results document that E006AA cells are indeed tumorigenic but vulnerable to NK cell killing.
Because of their life style, these organisms are highly vulnerable to somatic cell parasitism that can even lead to germ line invasion, "the evolutionary equivalent of death" [4].
