Sentence examples for vulnerable to aggregation from inspiring English sources

α-synuclein is vulnerable to aggregation under pathological conditions and forms insoluble fibrils that are a characteristic of Lewy bodies, a pathological hallmark of the neurodegenerative diseases.

While changes in the conformation make proteins vulnerable to aggregation and degradation, little is known about synaptic chaperones which counteract these processes.

Thus, the presence of αB-crystallin has shown significant inhibition of protein aggregation, although cells expressing αA162 still remained vulnerable to aggregation.

Although input output life cycle inventory (I O LCI) model enables economy-wide footprint calculations, the model is vulnerable to sector aggregation and is thus unsuitable for individual product analysis.

Our findings suggest that fibril formation of αSynuclein promotes the progressive degeneration of nigral DA neurons as found in PD patients and show that invertebrate and mammalian DA neurons are differently vulnerable to αSynuclein aggregation.

The synthesis of a particular drug LMWP conjugate requires careful design and a high degree of skill partly because LMWP have many active groups and are very vulnerable to self-aggregation.

Neurons are found to be particularly vulnerable to toxic stress from aggregation-prone proteins such as α-synuclein.

The physiological structures of neurons render them particularly vulnerable to motor protein malfunction, protein aggregation, and mitochondrial dysfunction.

Such violations are common in real-world voting rules, and they make preference aggregation potentially vulnerable to strategic voting and/or strategic agenda setting.

Such adaptations may also underlie proteostasis in other cell types, i.e. postmitotic muscle and neuronal cells that are vulnerable to the cytotoxic consequences of protein aggregation.

In the case of signal-blind (lasR) mutants, it is also possible that their inability to QS even in the presence of wild-type bacteria made them individually more vulnerable to predation even when associated with an aggregation.