Sentence examples for vulnerabilities of cells from inspiring English sources

The next challenge will be to identify the vulnerabilities of cells that have reduced regulatory subunits.

Suppression of DRP1 increased the vulnerability of cells to OGD and global ischemia due to amplified mitochondria-mediated injury (Zuo et al., 2016).

Protective Zhang et al. (2014) Male Sprague-Dawley rats CA3 neurons Primary hippocampal neurons IPC OGD Suppression of DRP1 increases the vulnerability of cells to OGD and global ischemia due to amplified mitochondria mediated injury.

The hyper-expression of ER-related molecular chaperons in sh2B5+2B5 R195H) cells under mild stress conditions further demonstrates the remarkable effect of this eIF2B mutation on the sensitivity and vulnerability of cells of the oligodendroglial lineage to ER stress.

As a whole, the results suggest a vulnerability of cells without Blm10.

Further study is necessary to determine the exact mechanisms that lead to the irradiation vulnerability of cells with long telomeres.

Therefore, RanBP9 appears not to induce overt cell death under normal culture conditions but increases the vulnerability of cells to undergo cell death under stressed conditions.

LRRK2 has been shown to modify the vulnerability of cells to mitochondrial dysfunction, with PD mutant forms of LRRK2 promoting mitochondrial dysfunction (Saha et al., 2009).

The vulnerability of cells for ionizing radiation largely depends on the rate of cell proliferation, the total dose of radiation, the fractionation scheme, and the capability of the cells to repair DNA damage [ 7].

These results taken together indicate that RanBP9 increases the vulnerability of cells to undergo apoptosis and mitochondrial dysfunction even under conditions where overt cell death is not readily detectable.

Over-expression of miR-9, let-7 g [ 54], miR-100, miR-101, miR-181a, or miR-421 has been shown to enhance the vulnerability of cells to IR-induced injury [ 55] and direct cells towards an apoptotic pathway.