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Figure 5 Central Arctic (mn km 2 ), cross-validation period (2010-11) actual vs fitted, and out-of-sample predictions to end 2014.

Figure 7 Greenland Sea (mn km 2 ), cross-validation period (2010-11) actual vs fitted, and out-of-sample predictions to end 2014.

Figure 8 Entire Arctic combined forest (mn km 2 ), cross-validation period (2010-11) actual vs fitted, and out-of-sample predictions to end 2014.

Residuals vs fitted; increase spread of residuals with increment of fitted values (predicted length of stay).

Plotting the inverse of τ vs [ATP] and fitting to the Michaelis Menten equation, we obtained KM = 110 ± 17 μM.

The reaction rates were calculated by plotting the fraction of GTP hydrolyzed vs time and fitting the data to a single exponential curve.

Furthermore, for the G_CG_G/C_C system, the Δ H°'s differed by 34% when determined by 1/ TM vs ln CT/4) and by fitting melting curves, but Δ G°37 of −8.89 kcal/mol from FCA was close to the values of −8.37 and −9.00 kcal/mol from melting curves (Table 2).

Thus, there is no warrant to worry about the quadratic vs linear regression fits shown in Figs. 4a and b.

The resultant data sets (normalized intensity vs temperature) were fitted with a third order polynomial, as was previously performed for temperature measurement with RhB.

For each cell sample, the TM data were plotted vs time and fitted to a monoexponential function: where t is the incubation time after X-ray exposure; TM0 and TMR are the initial repairable TM and residual (i.e. irreparable) TM, respectively; and τ0.5 is the repair half-time, that is, the time required for cells to restitute 50% of the DNA damage.

This selection can be performed by VS through small compound databases, fitting a known pharmacophore and/or a 3D structure of the target [ 31, 32].

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