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This may lead to overestimation of the variation in the volume of trials on different diseases but underestimation of the correlation between the volume of trials and the burden of disease.
Prospective trial registration has been heavily endorsed, and the volume of trials registered appears to be increasing [ 26- 28].
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The collection will be published starting in June and will be in two parts; 80 volumes of trial records, to be followed by 50 additional volumes of archival materials and references, reported the China Culture News, a newspaper owned by the Ministry of Culture.
Finally, as the volume of clinical trials grows, the need to manage multiple clinical trials at once poses additional challenges.
This finding is inconsistent with the observation that the volume of adult trials is growing at a faster rate than pediatric trials [ 5].
Extra regulation relating to drug trials may be due to history (visibility of drug related harms), the large volume of drug trials, and the strong financial power of the drug industry and its central role in drug research.
Due to the high volume of drug trials, strong commercial interests, tighter control traditionally, and problems related to the European Union (EU) Clinical Trials Directive, a special focus has been placed on drug research.
4 An increasing volume of published trials of psychosocial intervention programmes for preschool children with ASD have been seen in recent years.
Given the growing volume of clinical trials and medical technology transfer to African countries, it is of great concern that 28 (60 %) countries do not have a law regulating research, development and innovation.
28 29 And the overwhelming volume of controlled trials, many redundant or irrelevant to clinical practice, has led to calls for discipline in selecting study topics and streamlining the systematic review process.
Such adoption would also have the benefit of generating a volume of specific trials that would be available for future comparison in meta-epidemiological studies: by comparing the outcome of RCTs, which have adopted the above considerations with those that have not.
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CEO of Professional Science Editing for Scientists @ prosciediting.com